Senior Manager/Manager, CRO and KOL Alliances (Contract to Hire)

Our Mission Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission . Diversity at Altos Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list.  At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment. What You Will Contribute To Altos We are seeking a highly strategic, operationally sound, and business-savvy Senior Manager/Manager, CRO & KOL Alliances to lead the identification, qualification, and ongoing management of our external R&D ecosystem. In this high-visibility role, you will be responsible for scouting, vetting, and managing top-tier Contract Research Organizations (CROs) and Key Opinion Leaders (KOLs) across global biopharma, academia, and specialized research institutes. Role Purpose: To build and maintain an agile, elite network of external partners and scientific advisors, ensuring high quality and cost efficiency, to support our scientific strategic programs.  Manage the full CRO engagement lifecycle from scientific scoping, competitive selection, schedule of work design through to contract award and ongoing data review against pre-agreed quality and reporting standards, securing and overseeing a significant outsourced research program. Lead the onboarding, governance, and strategic direction of KOL networks, leveraging expert input across translational, clinical, and regulatory pathways to accelerate pipeline milestones. Key Responsibilities CRO Strategy & Selection Partner with scientific and program leads and internal functions to identify where outsourcing adds the most value (e.g., large-animal models, disease model optimization, GLP/non‑GLP studies). Partner with IVTS to lead the evaluation and selection of CROs, including feasibility assessments, capabilities reviews, site qualification, and compliance reviews (e.g., GCP, GLP, animal welfare/IACUC, IP protection). Design and execute rigorous vetting frameworks for CROs, evaluating scientific rigor, technical capabilities, quality assurance standards, capacity, turnaround times, and regulatory compliance. Study Design Translation & SOW Development Partner with scientific leads to translate scientific goals into structured, executable study plans and SOWs. Align internally on study objectives, endpoints, timelines, and decision points before engagement with CROs. Ensure study designs include clear go/no‑go criteria and data packages that directly inform next steps for the program. Scientific Operational Oversight Serve as the primary operational point of contact for CROs, coordinating timelines, milestones, and deliverables, as well as operational bottlenecks, timeline delays, or performance disputes with CROs and consultants. Chair regular check-ins with CROs, scientific leads and internal functions to review progress, risks, and adjustments to scope or timelines. Track sample logistics, bioanalytical plans, and data transfer to ensure downstream analyses can proceed without delay. Business Operations In collaboration with Legal and Procurement lead(s), assist in the drafting, negotiation, and execution of Master Services Agreements (MSAs), Statements of Work (SOWs), Consulting Agreements, and Material Transfer Agreements (MTAs). In partnership with Legal and Procurement, act as Subject Matter Expert (SME) to assist in pricing and term negotiations, benchmarking rates against industry standards to secure favorable, ROI-driven agreements. In collaboration with Procurement lead(s)the Request for Proposal (RFP) process from end to end, defining scope, gathering scientific requirements, and soliciting competitive bids from prospective vendors. Build and manage annual CRO/KOL spend forecasts in partnership with Finance. Track actual spend across the strategic portfolio. Quality, Compliance & Risk Management Ensure that CRO activities meet internal quality expectations and relevant regulatory/ethical standards (e.g., IACUC, GLP where applicable). Proactively identify risks (technical, operational, or timeline) and drive mitigation plans in collaboration with internal and external teams. Support audit readiness and documentation requirements for key studies. KOL Engagement & Advisory Board Management Identify, map, and qualify top-tier key opinion leaders (KOLs), academic pioneers, and scientific experts based on publication impact and therapeutic expertise. Assist in the coordination of the end-to-end vendor onboarding and execution of Consulting Agreements, MTAs, and advisor terms in close partnership with Legal, Finance, and program leads.  Lead the setup, operational cadence, and meeting governance for program-level External Advisory Boards (EABs) and specialized expert panels. Drive EAB and KOL engagements to harvest high-value scientific input that directly shapes translation, clinical development plans, IP strategy, and regulatory pathways. Synthesize advisory insights into actionable R&D takeaways, ensuring external scientific recommendations are seamlessly integrated into internal program decisions and milestones. Cross‑Functional Collaboration & Communication Work closely with biology, in vivo, pharmacology, tech ops, and program management to align on priorities and resource allocation for outsourced work. Provide clear, concise updates on study status, risks, and decisions to project teams and leadership. Help create playbooks, templates, and best practic