Senior Director, PMO Strategic Portfolio Management & AI Innovation

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: Seeking a dynamic Senior Director to join our Program Management Operations (PMO) team. Reporting to the Executive Director, Portfolio Strategy & PMO, this role is critical in driving AI-enabled portfolio strategy initiatives, overseeing comprehensive portfolio reporting, and leading the planning and execution of strategic and operational initiatives across Insmed's portfolio. This role offers an exciting opportunity to leverage cutting-edge AI technologies and data analytics to optimize portfolio decisions, transform reporting capabilities, and contribute to bringing innovative therapies to patients with serious diseases. What You'll Do: In this role, you will design and execute strategic initiatives that optimize portfolio performance and resource allocation. Additionally, you will collaborate with cross-functional teams to integrate AI and machine learning capabilities into portfolio management and reporting processes You will also have responsibility for: Design and implement AI-enabled reporting frameworks that automate data collection, analysis, and visualization Develop advanced analytics dashboards and predictive modeling tools for portfolio performance monitoring Leverage AI/ML technologies to identify portfolio-level risks, trends, opportunities, and strategic insights from reporting data Establish standardized reporting metrics, KPIs, and governance processes across the portfolio Lead the development and implementation of AI-driven portfolio strategy frameworks and decision-making tools Support senior leadership in strategic planning and portfolio optimization decisions based on data-driven insights Provide strategic oversight and guidance on portfolio prioritization and resource allocation Lead operational excellence initiatives across the PMO organization Identify opportunities for process improvement and automation using AI/ML technologies Develop and maintain portfolio analytics platforms that enable real-time decision-making Manage complex, multi-functional strategic projects from conception to completion Coordinate activities across Business Development, Program Management, Commercial, Regulatory Affairs, Medical Affairs, Technical Operations, Clinical Development, and Finance Who You Are: You have an advanced degree in business, engineering, data science, life sciences, or related field, and a minimum 10-12 years of strategic planning, portfolio management, or management consulting experience, with at least 5 years in pharmaceutical/biotechnology industry Additionally you have: Proven experience with AI/ML applications in business strategy, portfolio management, or reporting/analytics Strong understanding of drug development processes and pharmaceutical business modelsExpertise in data analytics, predictive modeling, business intelligence tools, and reporting platforms Experience with portfolio reporting, performance measurement, and executive-level communications Entrepreneurial self-starter with a proven track record of success in fast-paced environments Well-developed technical skills (Python/R, SQL, Tableau/PowerBI, Excel, PowerPoint, MS Teams/SharePoint) Nice to have: MBA or advanced degree in data science, AI/ML, or related technical field Experience in respiratory diseases, immunology & inflammation, neurology/neuroscience, and/or rare diseases Knowledge of AI/ML platforms and tools (TensorFlow, PyTorch, cloud-based ML services) Project Management Professional (PMP) or similar certification Experience with portfolio optimization and resource allocation methodologies Background in business intelligence, data visualization, and automated reporting system Travel Requirements This role requires occasional domestic travel approximately                         Where You’ll Work   This is a hybrid role based out of our Bridgewater, NJ Headquarters. You’ll work remotely most of the time, with in-person collaboration when it matters most. #LI-SK1 #LI-SK - Hybrid Pay Range: $214,000.00-292,000.00 Annual Life at Insmed At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself. Highlights of our U.S. offerings include: Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP) Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back Eligibility for specific programs may vary and is subject to the terms and conditions of each plan