Research Associate/Senior Research Associate, Cell Engineering
Colossal Biosciences · Dallas–Fort Worth, TX
📍 Dallas, TXvia greenhousePosted 2026-09-18
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An affiliate of Colossal is looking for a talented research associate in cell biology with an interest in the derivation, characterization, and gene editing in non-model mammalian organisms. You will work closely with other lab team members in efforts to innovate on protocols of genome editing, reprogramming and lineage differentiation using cutting edge technologies.
This position is based on-site in Dallas, TX. Relocation assistance is available.
Duties and Responsibilities:
Derive and characterize stable cell lines from primary tissues
Microdissection skills for cell line derivations
Test novel cell culture conditions and delivery methods to optimize gene editing
Expand clonal cell lines for cryopreservation, genotyping and QC assays
Work with team members to interrogate targeting, genotyping and QC workflows
Assist with making edited cell lines that meet quality control criteria for downstream SCNT
Schedule, analyze and execute experiments to deliver on project milestones
Attend lab meetings, prepares reports and presentations on the progress of projects
Demonstrate great organizational skills and excellent laboratory record maintenance
Required Skills and Abilities:
Experience in primary cell line derivation, culture optimization and cryopreservation
Experience with electroporation and transfection to maximize gene delivery and viability
Experience immunostaining cells for flow cytometry and fluorescent microscopy
Exceptional aseptic technique as antibiotic free cultures are standard
Organized and comfortable multi-tasking to deliver on concurrent projects on time
Strong written and oral communication skills, as well as creative problem-solving skills
Preferred Skills and Abilities:
Experience with high throughput imaging platforms and data analysis
Experience with automated cell culture systems
Experience with stem cell culture, such as mouse embryonic stem cells (mESC) or induced pluripotent stem cells (iPSC)
Education and Experience:
BA/BS/MA/MS in biological sciences, bioengineering, molecular biology, genetics, or any science related field.
What Colossal Offers Full-Time Employees:
Medical, dental, and vision coverage
Excellent paid time off and company holidays so you can rest and recharge
Flexible spending accounts (FSA)
Company matched 401k retirement plan
Paid parental leave at 100% salary for up to 12 weeks
Education reimbursement
An opportunity to help us return the Earth to a healthier state
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
EEO is the Law
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.
Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:
#1 on the 50 Best Startups to Work For in Dallas in 2023!
100 Best Midsize Places to Work in Dallas in 2024 & 2025
100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.
Built In 2026 Award Lists
Great Place to Work Certification Page
Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.
Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!
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