Procurement Manager
Xaira Therapeutics · San Francisco Bay Area
📍 South San Francisco, California, United States💰 $124,000 - $155,000via greenhousePosted 2026-09-21
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About Xaira Therapeutics
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
The Role
Xaira is seeking a Procurement Manager at the leading edge of the function — a builder who treats procurement as a commercial engine and a proving ground for AI-enabled operations. You're obsessed with stakeholders: scientists, engineers, and business partners are your customers, and their success is your scoreboard. You'll inherit a strong foundation but you have an obsession to drive the function beyond the empirical high-bar.
What You'll Do
Operations Leadership
Own end-to-end procurement operations: P2P process, sourcing, and technology enablement across all goods and services
Drive adoption of our contract-first CLM framework while reducing cycle times
Run procurement as a service business, with stakeholder experience as a core focus
Support Accounting: PO hygiene, invoice-match resolution, accruals, vendor master data and close activities
AI Enablement
Pilot and scale AI across the lifecycle: contract analysis, spend classification, supplier intelligence, negotiation prep, workflow automation
Make Xaira's procurement a showcase for AI-augmented operations — measured in cycle time, coverage, and cost
Translate the emerging procure-tech landscape into practical and adopted tooling
Supplier Engagement & Negotiations
Lead sourcing events and negotiations across core life-sciences suppliers
Structure agreements that protect Xaira's flexibility: competitive tension, cancellation frameworks and leading engagement terms
Build supplier relationships that scale: performance management, risk monitoring and strategic partnerships
Procure-Tech, Data & Analytics
Drive build-vs-buy decisions across the stack (P2P, CLM, sourcing, cost savings/avoidance) with an emphasis toward lean, high-leverage solutions
Build spend analytics that turn data into decisions: category insights, supplier concentration, budget-to-actual
Own data integrity across procurement and P2P systems
What You Bring
5+ years in procurement, strategic sourcing, or supply chain; biotech, pharma, or high-growth tech preferred
Proven negotiation results on complex service agreements (CRO, services, and technology)
Hands-on with modern procurement tools (Ironclad, Coupa, NetSuite, Ramp) and curiosity about what replaces them
Practical AI fluency applied to real workflows — you can point to processes you've automated
Strong analytics: spend analysis, dashboarding, supplier ecosystems, advanced metrics and analytics giving Xaira leverage as a competitive advantage among Xaira’s peer group
Stakeholder obsession - Building trust through accountability and delivery making Procurement an invaluable business partnership
Concise, executive-ready communication
Entrepreneurial: you find the gap, propose the fix, and ship it
Why This Role Matters
Every dollar and every week Procurement saves is capacity redirected toward discovering new medicines. If you want to build the most advanced Procurement function in biotech, this is the seat.
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $124,000 - $155,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.
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