Director, RDU IT Business Partner, Commercial - Alexion

WHY JOIN US? At Alexion, a division of AstraZeneca, we are driven by a shared purpose to transform the lives of people affected by rare and devastating diseases. By combining deep expertise in rare disease with the scale, science, and innovation of AstraZeneca, we are working to deliver meaningful advances for patients and families with significant unmet needs. Join us at an exciting time as we continue to evolve how technology, data, digital capabilities, and AI support our Commercial organization. You will have the opportunity to work closely with business and technology leaders, shape solutions that enable new product launches and commercial transformation, and help turn emerging technologies into measurable outcomes for patients and the business. Our culture is built on collaboration, innovation, and continuous learning. We encourage our people to challenge convention, explore new possibilities, and bring forward ideas that can improve how we work and how we serve patients. As part of Alexion, you will have the opportunity to make an impact in a highly specialized area of healthcare while benefiting from the capabilities and global reach of AstraZeneca. Hybrid Policy We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and meaningful in-person collaboration. This role is based in Boston, MA, with employees expected to work from the office three days per week , creating opportunities for teams to connect, collaborate, and solve complex challenges together. Introduction As Director, RDU IT Business Partner, US Commercial, you will serve as a senior business-facing technology partner, shaping and delivering technology, data, digital, and AI-enabled capabilities that support commercial priorities, launch readiness, commercial transformation, and improved patient outcomes. This position is based in Boston, MA, and may require up to 20% travel. About the Role The Director, RDU IT Business Partner, US Commercial will serve as a senior IT Business Partner for the US Commercial organization, with a defined portfolio spanning Commercial business functions, Commercial Training, Rare Disease Therapy Area teams, launch, Finance, Commercial Operations, Market Access, and enabling functions and AI-enabled transformation. This role will build trusted relationships with senior Commercial stakeholders, shape the multi-year technology and AI roadmap for assigned business areas, lead demand prioritization, steward portfolio health, and partner across IT, Digital, Data, AI, Architecture, Cybersecurity, Privacy, Compliance, Finance, Service Delivery, and external partners to deliver measurable business outcomes. Key Responsibilities Serve as a senior IT Business Partner and trusted advisor for assigned US Commercial business areas, aligning technology, data, digital, and AI roadmaps to business priorities. Build and maintain trusted relationships with senior stakeholders across US Commercial, Commercial Training, Rare Disease Therapy Area teams, launch, Finance, Commercial Operations, Market Access, and enabling functions. Partner with business leaders to translate strategic objectives into capability roadmaps, prioritized demand, investment options, and measurable outcomes. Steward assigned Commercial IT portfolio activities, including demand intake, prioritization, funding alignment, risks, dependencies, value realization, ServiceNow visibility, and executive reporting. Lead disciplined business capability mapping and technology roadmap development, ensuring roadmaps reflect business strategy, process maturity, data readiness, AI opportunity, and adoption needs. Support Market Access and GTN priorities at the portfolio level by translating key business needs into scalable, compliant technology and data-enabled solutions. Ensure assigned commercial solutions include appropriate governance, compliance, privacy, financial controls, adoption planning, and measurable value outcomes. Lead launch technology planning for new products, indications, and therapy area priorities with Sales, Marketing, Commercial Training, Market Access, and business operations. Lead through influence across business, IT, data, AI, architecture, delivery, and vendor teams; coach colleagues on business partnering, AI literacy, portfolio governance, executive communication, and value realization. AI-Ready Business Partner Responsibilities Enable AI for the business by identifying, framing, prioritizing, and scaling high-value AI, GenAI, agentic AI, automation, analytics, and data product opportunities across US Commercial workflows. Translate AI ideas into business-ready use cases with clear problem statements, target users, data requirements, operating model impacts, success measures, risks, and adoption requirements. Drive AI-enabled business outcomes across commercial decision support, launch readiness, Commercial Training enablement, executive reporting, forecasting support, customer engagement, and portfolio prioritization. Champion responsible AI adoption by partnering with Data, AI, Architecture, Cybersecurity, Privacy, Legal, Compliance, and business stakeholders to define explainability, traceability, human oversight, auditability, security, and value measurement requirements. Move the business from AI experimentation to measurable business impact by defining baselines, success metrics, adoption targets, governance requirements, and continuous improvement loops. Model AI-enabled business partnering by using approved AI tools and LLM-enabled workflows to improve stakeholder preparation, meeting synthesis, portfolio reporting, roadmap development, risk identification, executive communication, and follow-through. Use AI-assisted analysis to improve demand intake, synthesize stakeholder feedback, compare requirements, identify duplicate or overlapping requests, and generate clearer business problem statements. A